Disease Topics:Zika virus

Zika virus spreads to people primarily through the bite of an infected Aedesspecies mosquito (Ae. aegypti and Ae. albopictus). People can also get Zika through sex with an infected man, and the virus can also be passed from a pregnant woman to her fetus. The most common symptoms of Zika are fever, rash, joint pain, and conjunctivitis (red eyes). The illness is usually mild with symptoms lasting for several days to a week after being bitten by an infected mosquito. People usually don’t get sick enough to go to the hospital, and they very rarely die of Zika. For this reason, many people might not realize they have been infected. However, Zika virus infection during pregnancy can cause a serious birth defect called microcephaly, as well as other severe fetal brain defects. Once a person has been infected, he or she is likely to be protected from future infections.


Symptoms

·         Many people infected with Zika virus won’t have symptoms or will only have mild symptoms. The most common symptoms of Zika are fever, rash, joint pain, or conjunctivitis (red eyes). Other common symptoms include muscle pain and headache. The incubation period (the time from exposure to symptoms) for Zika virus disease is not known, but is likely to be a few days to a week.

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o    See your doctor or other healthcare provider if you are pregnant and develop a fever, rash, joint pain, or red eyes within 2 weeks after traveling to an area with Zika. Be sure to tell your doctor or other healthcare provider where you traveled.

·         The illness is usually mild with symptoms lasting for several days to a week.

·         People usually don’t get sick enough to go to the hospital, and they very rarely die of Zika. For this reason, many people might not realize they have been infected.

·         Zika virus usually remains in the blood of an infected person for about a week but it can be found longer in some people.

·         Once a person has been infected, he or she is likely to be protected from future infections.

Diagnosis

·         The symptoms of Zika are similar to those of dengue and chikungunya, diseases spread through the same mosquitoes that transmit Zika.

·         See your doctor or other healthcare provider if you have the symptoms described above and have visited an area with Zika.

·         If you have recently traveled, tell your doctor or other healthcare provider when and where you traveled.

o    A blood or urine test can confirm a Zika infection

·         Your doctor or other healthcare provider may order blood tests to look for Zika or other similar viruses like dengue or chikungunya.

Complications of Zika virus disease

After a comprehensive review of evidence, there is scientific consensus that Zika virus is a cause of microcephaly and Guillain-Barré syndrome. Intense efforts are continuing to investigate the link between Zika virus and a range of neurological disorders, within a rigorous research framework.

Diagnosis

Infection with Zika virus may be suspected based on symptoms and recent history of travel (e.g. residence in or travel to an area with active Zika virus transmission). A diagnosis of Zika virus infection can only be confirmed through laboratory tests on blood or other body fluids, such as urine, saliva or semen.

 

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Treatment
  • There is no vaccine to prevent or medicine to treat Zika virus.
  • Treat the symptoms:
  • Get plenty of rest.
  • Drink fluids to prevent dehydration.
  • Take medicine such as acetaminophen (Tylenol®) or paracetamol to reduce fever and pain.
  • Do not take aspirin and other non-steroidal anti-inflammatory drugs (NSAIDS) until dengue can be ruled out to reduce the risk of bleeding.
  • If you are taking medicine for another medical condition, talk to your doctor or other healthcare provider before taking additional medication.
  • During the first week of infection, Zika virus can be found in the blood and passed from an infected person to a mosquito through mosquito bites.
  • An infected mosquito can then spread the virus to other people.

Transmission
Zika virus is primarily transmitted to people through the bite of an infected mosquito from the Aedes genus, mainly Aedes aegypti in tropical regions. Aedes mosquitoes usually bite during the day, peaking during early morning and late afternoon/evening. This is the same mosquito that transmits dengue, chikungunya and yellow fever. Sexual transmission of Zika virus is also possible. Other modes of transmission such as blood transfusion are being investigated.
Treatment
Zika virus disease is usually mild and requires no specific treatment. People sick with Zika virus should get plenty of rest, drink enough fluids, and treat pain and fever with common medicines. If symptoms worsen, they should seek medical care and advice. There is currently no vaccine available.
Prevention
Protection against mosquito bites is a key measure to prevent Zika virus infection. This can be done by wearing clothes (preferably light-coloured) that cover as much of the body as possible; using physical barriers such as window screens or closing doors and windows; sleeping under mosquito nets; and using insect repellent containing DEET, IR3535 or icaridin according to the product label instructions. Special attention and help should be given to those who may not be able to protect themselves adequately, such as young children, the sick or elderly. Travellers and those living in affected areas should take the basic precautions described above to protect themselves from mosquito bites.
It is important to cover, empty or clean potential mosquito breeding sites in and around houses such as buckets, drums, pots, gutters, and used tyres. Communities should support local government efforts to reduce mosquitoes in their locality. Health authorities may also advise that spraying of insecticides be carried out.Sexual transmission of Zika virus has been documented in several different countries. To reduce the risk of sexual transmission and potential pregnancy complications related to Zika virus infection, the sexual partners of pregnant women, living in or returning from areas where local transmission of Zika virus occurs should practice safer sex (including using condoms) or abstain from sexual activity throughout the pregnancy.
People living in areas where local transmission of Zika virus occurs should also practice safer sex or abstain from sexual activity. In addition, people returning from areas where local transmission of Zika virus occurs should adopt safer sexual practices or abstain from sex for at least 8 weeks after their return, even if they don’t have symptoms. If men experience Zika virus symptoms they should adopt safer sexual practices or consider abstinence for at least 6 months. Those planning a pregnancy should wait at least 8 weeks before trying to conceive if no symptoms of Zika virus infection appear, or 6 months if one or both members of the couple are symptomatic.



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